Endothelial dysfunction of rabbit mesenteric artery in organ culture
نویسندگان
چکیده
منابع مشابه
Endothelial dysfunction in rat mesenteric resistance artery after transient middle cerebral artery occlusion.
Stroke triggers a local and systemic inflammatory response leading to the production of cytokines that can influence blood vessel reactivity. In this study, we aimed to assess whether cerebral ischemia/reperfusion could affect vasoconstriction and vasodilatation on mesenteric resistance arteries (MRA) from Wistar Kyoto rats. The right middle cerebral artery was occluded (90 min) and reperfused ...
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The vasodilating effects of flunarizine on smooth muscle strips of rabbit mesenteric artery have been investigated and compared with those of nifedipine. Flunarizine (30-300 nM) dose-dependently inhibited Ca2+-induced contractions in Ca2+-free solution containing 100 mM K+. Double reciprocal analysis showed that this inhibition was either competitive at low concentrations (30-100 nM; nifedipine...
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1. Explants of mammary gland from mid-pregnant rabbits were cultured in medium 199 containing insulin, prolactin and cortisol, and specific anti-casein immunoglobulin G was used to measure the amount, rate of synthesis and rate of degradation of casein in the explants in the presence of hormones and after removal of hormones from previously stimulated tissue. 2. The amount of casein in particle...
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INTRODUCTION: In vitro organ culture studies of the intervertebral disc (IVD) have been commonly used to understand the biologic and mechanical pathways contributing to disc degeneration. In particular, small animal models such as rat and rabbit have many advantages over large animals in an organ culture standpoint. Temporal and spatial stability of cell viability and extracellular matrix conte...
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Organ culture of blood vessel is a better technique to investigate the long-term effects of drugs. However, some functional changes may occur from freshly isolated vessel (Fresh). Mammalian/mechanistic target of rapamycin (mTOR) regulates smooth muscle differentiation and Ca(2+) mobilization. We thus investigated mechanisms of alteration in smooth muscle contractility after serum-free organ cul...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1997
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)44886-5